If you would like to explore the possibility of participating in a clinical trial at Guthrie, please call 1-800-836-0388.

As a Guthrie cancer patient you will have the unique opportunity to participate in one or more of some 100 clinical research trials that involve new treatments for many cancer types.

As a Guthrie patient you may have the unique opportunity to take part in clinical research trials for atrial fibrillation, congestive heart failure, lipid disorders, heart attack and many more cardiology disease states.

As a Guthrie patient you may have an opportunity to take part in clinical research trials for celiac disease, Crohn’s disease, ulcerative colitis, reflux disease, hepatitis and many more gastroenterology disease states.

Clinical trials study new ways to prevent, detect and treat disease. If you take part in research, you help advance new investigational medical therapies. 

Title: LungMap (Screening Protocol for Lung-Map):
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: SWOG
Details (Indentifier #): NCT03851445
Title: Molecular Analysis for Combination Therapy Choice
(ComboMATCH)
Department: Oncology
Diagnosis: Gastrointestinal - Colon-Rectal
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: NCI
Title: NRG-BR007: A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer
Department: Oncology
Diagnosis: Breast- Adjuvant
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: NRG
Details (Indentifier #): NCT04852887
Title: NRG-LU007: Randomized Phase II/III Trial of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR Trial
Department: Oncology
Diagnosis: Lung- Small Cell
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: NRG
Details (Indentifier #): NCT04402788
Title: OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy
Department: Oncology
Diagnosis: Breast
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: ALLIANCE
Details (Indentifier #): NCT05812807
Title: Preserve-003: Phase 3, Two-stage, Randomized Study of ONC-392 Versus Docetaxel in Metastatic Non-Small Cell Lung Cancers that Progressed on PD-1/PD-L1 Inhibitors
Department: Oncology
Diagnosis: Lung- Non-Small Cell
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: OncoC4
Details (Indentifier #): NCT05671510
Title: Prolocor PRL-0001
Department: Cardiology
Diagnosis: Cardiac - Miscellaneous
Sponsors: Prolocor
Title: S-11: A multicentre, prospective clinical study analysing outcomes of shoulder arthroplasty with SMR TT Hybrid Glenoid with or without SMR Cementless Finned Short Stem
Department: Orthopedic Surgery
Diagnosis: Orthopedics
Principal Investigator: Joseph Y. Choi, MD, PhD, MHA
Sponsors: Lima
Details (Indentifier #): NCT05314387
Title: S1706: A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy Versus Radiotherapy Alone for Inflammatory Breast Cancer
Department: Oncology
Diagnosis: Breast- Adjuvant
Principal Investigator: Thomas J Gergel, MD
Sub-Investigator(s):
Sponsors: SWOG
Details (Indentifier #): NCT03598257
Title: S1802, "Phase III Randomized Trial of Standard Systemic Therapy (SST) Versus Standard
Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor
in Metastatic Prostate Cancer)."
Department: Oncology
Diagnosis: Genito-urinary - Prostate
Principal Investigator: Joyson Poulose, MD
Sub-Investigator(s):
Sponsors: NCI
Details (Indentifier #): 03678025
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